Use este identificador para citar ou linkar para este item: http://www.alice.cnptia.embrapa.br/alice/handle/doc/1077504
Registro completo de metadados
Campo DCValorIdioma
dc.contributor.authorROJAS, T. C. G.
dc.contributor.authorMALUTA, R. P.
dc.contributor.authorKOENIGKAN, L. V.
dc.contributor.authorSILVEIRA, W. D. da
dc.date.accessioned2017-10-19T09:29:32Z-
dc.date.available2017-10-19T09:29:32Z-
dc.date.created2017-10-17
dc.date.issued2014
dc.identifier.citationPesquisa Veterinária Brasileira, Rio de Janeiro, v. 34, n. 2, p. 129-133, fev. 2014.
dc.identifier.urihttp://www.alice.cnptia.embrapa.br/alice/handle/doc/1077504-
dc.descriptionAvian pathogenic Escherichia coli (APEC) infections are responsible for significant losses in the poultry industry worldwide. A zoonotic risk has been attributed to APEC strains because they present similarities to extraintestinal pathogenic E. coli (ExPEC) associated with illness in humans, mainly urinary tract infections and neonatal meningitis. Here, we present in silico analyses with pathogenic E. coli genome sequences, including recently available APEC genomes. The phylogenetic tree, based on multi-locus sequence typing (MLST) of seven housekeeping genes, revealed high diversity in the allelic composition. Nevertheless, despite this diversity, the phylogenetic tree was able to cluster the different pathotypes together. An in silico virulence gene profile was also determined for each of these strains, through the presence or absence of 83 well-known virulence genes/traits described in pathogenic E. coli strains. The MLST phylogeny and the virulence gene profiles demonstrated a certain genetic similarity between Brazilian APEC strains, APEC isolated in the United States, UPEC (uropathogenic E. coli) and diarrheagenic strains isolated from humans. This correlation corroborates and reinforces the zoonotic potential hypothesis proposed to APEC.
dc.language.isoengeng
dc.rightsopenAccesseng
dc.subjectÁrvore filogenética
dc.subjectAvian pathogenic Escherichia coli
dc.subjectTipagem de sequência multilocus
dc.subjectAnálise in silico
dc.subjectGenes associados à virulência
dc.subjectMulti-locus Sequence Typing
dc.subjectPhylogenetic tree
dc.subjectVirulence genes
dc.titleIn silico phylogenetic and virulence gene profile analyses of avian pathogenic Escherichia coli genome sequences.
dc.typeArtigo de periódico
dc.date.updated2017-10-19T09:29:32Zpt_BR
dc.subject.thesagroEscherichia Colipt_BR
riaa.ainfo.id1077504
riaa.ainfo.lastupdate2017-10-17
dc.identifier.doihttp://dx.doi.org/10.1590/S0100-736X2014000200006
dc.contributor.institutionTHAÍS C. G. ROJAS, IB/Unicamp; RENATO P. MALUTA, IB/Unicamp; LUCIANO VIEIRA KOENIGKAN, CNPTIA; WANDERLEY DIAS DA SILVEIRA, IB/Unicamp.
Aparece nas coleções:Artigo em periódico indexado (CNPTIA)

Arquivos associados a este item:
Arquivo Descrição TamanhoFormato 
APInsilicoRojasetal2014.pdf462,4 kBAdobe PDFThumbnail
Visualizar/Abrir
Mostrar registro simples do item Visualizar estatísticas

FacebookTwitterDeliciousLinkedInGoogle BookmarksMySpace