Title:	Relative scalability of NoSQL databases for genotype data manipulation.
Authors:	ALMEIDA, A. L. SCHETTINO, V. J. BARBOSA, T. J. R. FREITAS, P. F. GUIMARÃES, P. G. S. ARBEX, W. A.
Affiliation:	WAGNER ANTONIO ARBEX, CNPGL.
Date Issued:	2018
Citation:	Revista de Informática Teórica e Aplicada, v. 25, n. 2, p. 93-100, 2018.
Description:	Abstract Genotype data manipulation is one of the greatest challenges in bioinformatics and genomics mainly because of high dimensionality and unbalancing characteristics. These peculiarities explains why Relational Database Management Systems (RDBMSs), the "de facto" standard storage solution, have not been presented as the best tools for this kind of data. However, Big Data has been pushing the development of modern database systems that might be able to overcome RDBMSs deficiencies. In this context, we extended our previous works on the evaluation of relative performance among NoSQLs engines from different families, adapting the schema design in order to achieve better performance based on its conclusions, thus being able to store more SNP markers for each individual. Using Yahoo! Cloud Serving Benchmark (YCSB) benchmark framework, we assessed each database system over hypothetical SNP sequences. Results indicate that although Tarantool has the best overall throughput, MongoDB is less impacted by the increase of SNP markers per individual.
NAL Thesaurus:	Bioinformatics Genotype
Keywords:	Database NoSQL Data Science SNP
DOI:	10.22456/2175-2745.79334
Type of Material:	Artigo de periódico
Access:	openAccess
Appears in Collections:	Artigo em periódico indexado (CNPGL)