Please use this identifier to cite or link to this item: http://www.alice.cnptia.embrapa.br/alice/handle/doc/1111456
Research center of Embrapa/Collection: Embrapa Pecuária Sudeste - Artigo em periódico indexado (ALICE)
Date Issued: 2019
Type of Material: Artigo em periódico indexado (ALICE)
Authors: NICIURA, S. C. M.
TIZIOTO, P. C.
MORAES, C. V.
CRUVINEL, G. G.
ALBUQUERQUE, A. C. A. de
SANTANA, R. C. M.
CHAGAS, A. C. de S.
ESTEVES, S. N.
BENAVIDES, M. V.
AMARANTE, A. F. T. do
Additional Information: SIMONE CRISTINA MEO NICIURA, CPPSE; Polyana Cristine Tizioto, NGS Soluções Genômicas; Caroline Valério Moraes, UFSCar; Giovanna Gabrielle Cruvinel, UNICEP; Ana Cláudia Alexandre de Albuquerque, FMVZ-UNESP; RAUL COSTA MASCARENHAS SANTANA, CPPSE; ANA CAROLINA DE SOUZA CHAGAS, CPPSE; SERGIO NOVITA ESTEVES, CPPSE; MAGDA VIEIRA BENAVIDES, CPPSUL; Alessandro Francisco Talamini do Amarante, IBB-UNESP.
Title: Extreme-QTL mapping of monepantel resistance in Haemonchus contortus.
Publisher: Parasites Vectors, v.12, n.403, p.1-11, 2019.
Language: en
Keywords: Anthelmintic resistance
Genome sequencing
Sheep gastrointestinal nematodes
F2 mapping
Description: Haemonchus contortus, a gastrointestinal nematode parasite of sheep, is mainly controlled by anthelmintics; the occurrence of anthelmintic resistance leads to treatment failures and increases economic burden. Because molecular mechanisms involved in drug resistance can be elucidated by genomic studies, an extreme quantitative trait locus (X-QTL) mapping approach was used to identify co-segregation of the resistance phenotype with genetic markers to detect the genome-wide variants associated with monepantel resistance in H. contortus.
NAL Thesaurus: Drug resistance
Data Created: 2019-08-20
Appears in Collections:Artigo em periódico indexado (CPPSE)

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