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dc.contributor.authorFERREIRA, M. R. A.eng
dc.contributor.authorFINGER, P. F.eng
dc.contributor.authorMAGALHÃES, C. G.eng
dc.contributor.authorCUNHA, C. E. P. daeng
dc.contributor.authorMOREIRA JÚNIOR, C.eng
dc.contributor.authorKICH, J. D.eng
dc.contributor.authorMORES, M. A. Z.eng
dc.contributor.authorMOREIRA, A. N.eng
dc.contributor.authorDELLAGOSTIN, O. A.eng
dc.contributor.authorCONCEIÇÃO, F. R.eng
dc.date.accessioned2019-11-06T18:09:52Z-
dc.date.available2019-11-06T18:09:52Z-
dc.date.created2019-11-06
dc.date.issued2019
dc.identifier.citationActa Scientiae Veterinária, v. 47, n. 1660, 2019.eng
dc.identifier.urihttp://www.alice.cnptia.embrapa.br/alice/handle/doc/1113965-
dc.descriptionAbstract: Mycoplasma hyopneumoniae is the etiological agent of the Swine Mycoplasmal Pneumonia (SMP), one of the most economically significant diseases in the swine industry worldwide. Commonly used vaccines for SMP control consist of inactivated whole cells (bacterins). These vaccines are efficacious against M. hyopneumoniae challenge, but do not prevent colonization by the pathogen or completely eliminate pneumonia. P97 adhesin is conserved in the M. pneumoniae virulent strains, therefore it is an attractive target to be used in recombinant vaccines against M. hyopneumoniae. The aim of the present study was to evaluate protection afforded by rLTB-R1, a recombinant chimera composed by LTB fused with the R1 repeat region of P97 adhesin of M. hyopneumoniae, in specific-pathogen-free (SPF) piglets vaccinated by intranasal or intramuscular route and challenged with a pathogenic strain of M. hyopneumoniae.eng
dc.language.isoengeng
dc.rightsopenAccesseng
dc.subjectPneumonia micoplasmática suínaeng
dc.subjectVacinação mucosaeng
dc.subjectAdesina P97eng
dc.subjectLTBeng
dc.titleProtection efficacy of the rLTB-R1 chimera against experimental swine mycoplasmal pneumonia.eng
dc.typeArtigo de periódicoeng
dc.date.updated2019-11-06T18:09:52Z
dc.subject.thesagroPneumoniaeng
dc.subject.thesagroMicoplasmaeng
dc.subject.thesagroVacinaeng
dc.subject.thesagroSuinoculturaeng
dc.subject.nalthesaurusMycoplasma hyopneumoniaeeng
dc.subject.nalthesaurusVaccinationeng
dc.subject.nalthesaurusAdhesinseng
riaa.ainfo.id1113965eng
riaa.ainfo.lastupdate2019-11-06
dc.identifier.doi10.22456/1679-9216.90862eng
dc.contributor.institutionMARCOS ROBERTO ALVES FERREIRA, UFPel; PAULA FONSECA FINGER, UNIPAMPA; CAROLINA GEORG MAGALHÃES, UFPel; CARLOS EDUARDO POUEY DA CUNHA, UFPel; CLÓVIS MOREIRA JÚNIOR, UFPel; JALUSA DEON KICH, CNPSA; MARCOS ANTONIO ZANELLA MORES, CNPSA; ÂNGELA NUNES MOREIRA, UFPel; ODIR ANTONIO DELLAGOSTIN, UFPel; FABRICIO ROCHEDO CONCEIÇÃO, UFPel.eng
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