Title:	Chemical composition and biological activities of the essential oils from Lippia alba and Lippia origanoides.
Authors:	SANTOS FILHO, L. G. A. dos REIS, K. B. dos SOUZA, A. S. Q. CANUTO, K. M. BRITO, E. S. de CASTRO, K. N. de C. PEREIRA, A. M. L. DINIZ, F. M.
Affiliation:	LUIZ G. A. DOS SANTOS FILHO, Universidade Federal do Delta do Parnaíba; RENATA B. DOS REIS, Universidade Federal do Delta do Parnaíba; ANA SHEILA Q. SOUZA, Universidade Federal do Ceará; KIRLEY MARQUES CANUTO, CNPAT; EDY SOUSA DE BRITO, CNPAT; KARINA NEOOB DE CARVALHO CASTRO, CNPGL; ALITIENE MOURA LEMOS PEREIRA, CPATC; FABIO MENDONCA DINIZ, CNPC.
Date Issued:	2023
Citation:	Anais da Academia Brasileira de Ciências, v. 95, n. 1, e20220359, 2023.
Description:	There is an increasing interest in essential oils extracted from Verbenaceae plant species as potential sources of biologically active compounds that could provide a starting point for designing novel phyto-pharmaceuticals in aquaculture. The present study was aimed to investigate the chemical composition, antioxidant activity, acute toxicity and antimicrobial effects against Vibrio parahaemolyticus of essential oils extracted from Lippia alba and L. origanoides. Approximately 23 components were identified and quantified by gas chromatography-mass spectrometry and flame ionization detection in each species? essential oil. The most predominant compounds were geranial (23.0%), limonene (17.0%) and neral (15.5%) in L. alba, and thymol (47.2%), p-cymene (16.0%) and E-caryophyllene (11.3%) in L. origanoides. The essential oils have antibacterial activity against Vibrio parahaemolyticus presenting Minimum Inhibitory Concentration (MIC) and Bactericidal Concentration (MBC) values between 156-625 µg mL-1. The essential oils also show antioxidant potential estimated by 1,1-diphenyl-2-picrylhydrazyl (DPPH) free radical scavenging assays, presenting IC50 of 60.16 mg mL-1 and 0.22 mg mL-1 for L. alba and L. origanoides EO, respectively. Both oils were classified as toxic to Artemia salina nauplii. Therefore, these essential oils may be useful for controlling pathogenic bacteria important to the aquaculture industry.
Thesagro:	Erva Cidreira Composição Química Lippia Alba Salva Óleo Essencial
NAL Thesaurus:	Lippia origanoides Chemical composition
Keywords:	Composição biológica Biological composition
DOI:	https://doi.org/10.1590/0001-3765202320220359
Type of Material:	Artigo de periódico
Access:	openAccess
Appears in Collections:	Artigo em periódico indexado (CNPAT)