Title:	Compatibility and cytotoxicity of poly(ε-caprolactone)/ polypyrrole-block-poly(ε-caprolactone) blend films in fibroblast bovine cells.
Authors:	SOUZA, N. L. G. D. de CAVALLINI, G. S. ALVES, T. T. PEREIRA, M. M. BRANDAO, H. de M. OLIVEIRA, L. F. C. de
Affiliation:	NELSON LUIS GONÇALVES DIAS DE SOUZA, UNIVERSIDADE FEDERAL DO TOCANTINS; GRASIELE SOARES CAVALLINI, UNIVERSIDADE FEDERAL DO TOCANTINS; TIAGO TEIXEIRA ALVES, UNIVERSIDADE FEDERAL DO TOCANTINS; MICHELE MUNK PEREIRA, UNIVERSIDADE FEDERAL DE JUIZ DE FORA; HUMBERTO DE MELLO BRANDAO, CNPGL; LUIZ FERNANDO CAPPA DE OLIVEIRA, UNIVERSIDADE FEDERAL DE JUIZ DE FORA.
Date Issued:	2024
Citation:	Polímeros, v. 34, n. 1, e20240007, 2024.
Description:	Polymer blends, derived from the combination of two or more polymers, yield novel materials with properties distinct from that of the original polymers. These materials have garnered interest in the medical field. However, for such applications the biocompatibility of the material must be evaluated. In this study, we prepared polymer blends from poly(ε-caprolactone) (PCL) and polypyrrole-block-poly(caprolactone) (PPy-b-PCL) using the casting method. The observed compatibility resulted from specific interactions between the carboxylic group of PCL and the amine group of PPy-b-PCL, as well as between the pyrrole ring of PPy-b-PCL and the CH2 group of PCL. Micro-Raman imaging revealed homogeneity in surface morphology, whereas thermogravimetric analysis indicated that the formation of polymer blends enhances the material’s thermal stability. Importantly, the results demonstrated that the addition of PPy-b-PCL does not affect the cytotoxicity to bovine fibroblasts, suggesting their biocompatibility and potential application in cattle veterinary devices.
Thesagro:	Polimerização Bovino
NAL Thesaurus:	Biocompatibility Cell proliferation
Keywords:	Polymer blends Biocompatibilidade Proliferação celular
DOI:	https://doi.org/10.1590/0104-1428.20230082
Type of Material:	Artigo de periódico
Access:	openAccess
Appears in Collections:	Artigo em periódico indexado (CNPGL)