Title:	Enzymatic synthesis of aromatic biobased polymers in green, low-boiling solvents.
Authors:	SALUM, T. F. C. DAY, D. SHERWOOD, J. PELLIS, A. FARMER, T. J.
Affiliation:	THAIS FABIANA CHAN SALUM, CNPAE; DANIEL DAY, UNIVERSITY OF YORK; JAMES SHERWOOD, UNIVERSITY OF YORK; ALESSANDRO PELLIS, UNIVERSITY OF GENOVA; THOMAS JAMES FARMER, UNIVERSITY OF YORK, DEPARTMENT OF CHEMISTRY.
Date Issued:	2024
Citation:	Journal of Biotechnology, v. 396, p. 1-9, 2024.
Description:	Given the urge to accelerate the substitution of petrol-derived solvents not only in more traditional fields like pharmaceuticals, personal care, or electronics but also in innovative research processes, this work focuses on the utilisation of four biobased solvents as media for the enzymatic synthesis of aliphatic-aromatic polyesters. As building blocks, the lignin-derived diethyl-2,4-pyridinedicarboxylate was selected as the potentially biobased, aromatic component while more classical diols such as 1,4-butanediol and 1,8-octanediol were used as the aliphatic portion. Results show that among the tested green solvents (cyclohexanone, phenetole, anisole and eucalyptol), the most suitable medium for lipase B from Candida antarctica-catalysed polycondensation reactions was eucalyptol that allowed reach monomer conversions >95 % and number average molecular weights up to 3500 g⋅mol 1. On the other hand, cyclohexanone led to the lowest monomer conversions (<80 %) and molecular weights (Mn<500 g⋅mol 1) confirming once again the unsuitability of ketone-containing solvents for enzymatic esterification and transesterification reactions. The lipase could be used up to three times, in eucalyptol as a solvent, without a significant decrease in monomer conversion or molecular weight.
NAL Thesaurus:	Biomass
Keywords:	Pyridinedicarboxylic acids Eucalyptol Enzymatic polycondensation Green solvent Sustainable polymer
DOI:	https://doi.org/10.1016/j.jbiotec.2024.10.003
Type of Material:	Artigo de periódico
Access:	openAccess
Appears in Collections:	Artigo em periódico indexado (CNPAE)