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DC Field | Value | Language |
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dc.contributor.author | OTA, E. do C. | |
dc.contributor.author | INOUE, L. A. K. A. | |
dc.contributor.author | ZANON, R. B. | |
dc.contributor.author | SUARES, F. S. | |
dc.contributor.author | SILVA, T. S. de C. | |
dc.date.accessioned | 2025-02-28T15:28:11Z | - |
dc.date.available | 2025-02-28T15:28:11Z | - |
dc.date.created | 2025-02-28 | |
dc.date.issued | 2024 | |
dc.identifier.citation | Pesquisa Agropecuária Gaúcha, v. 30, n. 1, p. 80-99, 2024. | |
dc.identifier.uri | http://www.alice.cnptia.embrapa.br/alice/handle/doc/1173534 | - |
dc.description | In fish challenge tests, there is no standardization in the concentration and analysis period of parameters. This study investigates the immunomodulatory and cytotoxic effects of A. hydrophila dose and post- immunostimulation periods on Nile tilapia. Four level of bacterial doses (1⁄2, 1⁄4, 1⁄8, and 0 LD50) were administered, and immune parameters, hematological data, and erythrocyte abnormalities were analyzed at 3, 7, 10, and 14 days post-infection (dpi). The highest respiratory burst, total globulins, and lysozyme activity were detected at 7 dpi. Considering the bacteria doses, the lysozyme activity was higher in the 1⁄8 LD50 and 1⁄4 LD50 of A. hydrophila. Erythrocytes, hematocrit, hemoglobin, leukocytes, lymphocytes, neutrophils, and monocytes counts remained unchanged. Ten days post-injection, the control group exhibited reduced abnormalities, showing a notable distinction from the 1⁄8 LD50 and 1⁄4 LD50 treatments, particularly in hooked and notched nuclei abnormalities. Mortality rates were higher in infected groups, peaking at different times with the highest in 1⁄2 LD50. For evaluating Nile tilapia immunity post A. hydrophila infection, it is recommended 1⁄4 LD50 dose and blood collection at 7 and 10 dpi for immunological parameters and abnormalities in Nile tilapia erythrocytes, respectively. | |
dc.language.iso | eng | |
dc.rights | openAccess | |
dc.subject | Tilapia do nilo | |
dc.subject | Imunomoduladores | |
dc.subject | Citotóxicos | |
dc.title | Aeromonas hydrophila dose and post-immunostimulation period as immunomodulatory effect indicator on Nile tilapia (Oreochromis niloticus) | |
dc.type | Artigo de periódico | |
riaa.ainfo.id | 1173534 | |
riaa.ainfo.lastupdate | 2025-02-28 | |
dc.identifier.doi | 10.36812/pag.202430180-99 | |
dc.contributor.institution | ERIKA DO CARMO OTA, BOLSISTA / EMBRAPA AGROPECUÁRIA OESTE, DOURADOS; LUIS ANTONIO KIOSHI AOKI INOUE, CPAO; RICARDO BASSO ZANON, UNIVERSIDADE FEDERAL DA GRANDE DOURADOS, DOURADOS; FERNANDA SOTOLANI SUARES, UNIVERSIDADE FEDERAL DA GRANDE DOURADOS, DOURADOS; TARCILA SOUZA DE CASTRO SILVA, CPAO. | |
Appears in Collections: | Artigo em periódico indexado (CPAO)![]() ![]() |
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File | Description | Size | Format | |
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800-Provas-3415-3-10-20241218.pdf | 1.16 MB | Adobe PDF | ![]() View/Open |