Title:	Hematological, biochemical and physiological evaluation of tilapia juveniles treated with organophosphate trichlorfon.
Authors:	GIL, J. A. CARDOSO, I. L. FERRI, G. H. SOARES, M. P. BALDIN, C. M. QUEIROZ, J. F. de ISHIKAWA, M. M.
Affiliation:	JULIANA AUGUSTA GIL, UNIVERSIDADE ESTADUAL DE CAMPINAS; ISRAEL LUZ CARDOSO, UNIVERSIDADE FEDERAL DE SÃO CARLOS; GIOVANNI HENRIQUE FERRI, UNIVERSIDADE ESTADUAL DE CAMPINAS; MICHELLY PEREIRA SOARES, UNIVERSIDADE FEDERAL DE SÃO CARLOS; CINTIA MANZATTO BALDIN, CENTRO UNIVERSITÁRIO DE JAGUARIÚNA; JULIO FERRAZ DE QUEIROZ, CNPMA; MARCIA MAYUMI ISHIKAWA, CNPMA.
Date Issued:	2025
Citation:	Studies in Environmental and Animal Sciences, v. 6, n. 2, p.e16255, 2025.
Description:	Abstract: Trichlorfon (TCF) is an organophosphate parasiticide commonly used in aquaculture to treat ectoparasites. However, studies across various fish species have reported adverse effects even at sublethal doses. This study assessed the hematological and biochemical responses of Nile tilapia juveniles (Oreochromis niloticus) following a one-hour exposure to a 0.5 mg L⁻¹ bath of a commercial TCF-based product. It also evaluated the fish's physiological recovery 28 hours after exposure. Results showed elevated plasma cortisol levels and a downregulation of glutathione-S-transferase (GST) activity in liver tissue among TCF-exposed fish compared to controls. Alterations in the leukogram of treated fish indicate an increased vulnerability to disease. These findings suggest that a 28-hour recovery period is insufficient to restore the physiological health of Nile tilapia juveniles after TCF exposure. The study highlights the importance of adopting best management practices (BMPs) when applying TCF treatments in aquaculture and underscores the need for further research on the short- and long-term physiological impacts of chemical treatments on fish.
Thesagro:	Tilápia Oreochromis Niloticus Parasitose Parasiticida Efeito Colateral Hematologia Glicose
NAL Thesaurus:	Tilapia (common name) Parasitoses Trichlorfon Adverse effects Blood glucose Ectoparasites Oxidative stress Physiological response
Keywords:	Cortisol plasmático Estresse oxidativo Ectoparasitas Resposta fisiológica Plasma cortisol
ISSN:	2764-0760
DOI:	https://doi.org/10.54020/seasv6n2-001
Type of Material:	Artigo de periódico
Access:	openAccess
Appears in Collections:	Artigo em periódico indexado (CNPMA)