Título:	Intensified multistep extraction of phenolic compounds from yerba mate.
Autoria:	ARANTES, M. S. T. LIMA, S. M. N. de DUSI, G. G. HELM, C. V. MAGALHAES, W. L. E. SILVA, V. R. da
Afiliação:	MATHEUS SAMPONI TUCUNDUVA ARANTES, UNIVERSIDADE FEDERAL DO PARANÁ; SARA MARIELE NOHR DE LIMA, UNIVERSIDADE FEDERAL DO PARANÁ; GIOVANA GONÇALVES DUSI, UNIVERSIDADE FEDERAL DO PARANÁ; CRISTIANE VIEIRA HELM, CNPF; WASHINGTON LUIZ ESTEVES MAGALHAES, CNPF; VÍTOR RENAN DA SILVA, UNIVERSIDADE FEDERAL DO PARANÁ.
Ano de publicação:	2026
Referência:	ACS Omega, v. 11, n. 6, p. 9816-9825, 2026.
Conteúdo:	In the current work, an alternative intensified methodology for the extraction of phenolic compounds from yerba mate is proposed, considering the use of sequential multistages. Conventional single-stage extraction was optimized in its key parameters (temperature and solid/liquid ratio), and its kinetics were evaluated. The multistage extraction process was evaluated considering two and four stages, considering the results on the antioxidant potential of the final extract. A scale-up simulation was conducted, considering the processing of 25 kg of yerba mate a day, and economic and environmental aspects were considered. The best extraction condition was achieved at 70 degrees C with 0.5 g yerba mate 100 mL-1 water. Intensified multistage processes and conventional ones resulted in final extracts with similar antioxidant potential (493.0-526.5 mg GAE L-1), highlighting that the three processes can be used for the obtention of the same product. Regarding the economic aspects, using the multistage extraction processes results in a considerable decrease in the Total Capital Investment of a yerba mate plant extract. Finally, environmental analysis shows that the multistep process is more eco-friendly than the conventional one, as it exhibits considerably lower energy consumption and lower CO2 emissions. The intensified multistage extraction process is a green and eco-friendly alternative to conventional extraction processes, with potential for implementation in several plant extract industries.
Thesagro:	Ilex Paraguariensis Folha Composto Fenólico Extração
NAL Thesaurus:	Phenolic compounds Yerba mate Compost extracts
Palavras-chave:	Erva mate
ISSN:	2470-1343
Digital Object Identifier:	10.1021/acsomega.5c10400
Tipo do material:	Artigo de periódico
Acesso:	openAccess
Aparece nas coleções:	Artigo em periódico indexado (CNPF)