Título:	Diversification of an emerging bacterial plant pathogen; insights into the global spread of Xanthomonas euvesicatoria pv. perforans.
Autor:	TIMILSINA, S. IRUEGAS-BOCARDO, F. JIBRIN, M. O. SHARMA, A. SUBEDI, A. KAUR, A. MINSAVAGE, G. V. HUGUET-TAPIA, J. C. KLEIN-GORDON, J. ADHIKARI, P. ADHIKARI, T. B. CIRVILLERI, G. BARRERA, L. B. T. de L. BERNAL, E. CRESWELL, T. C. DOAN, T. T. K. COUTINHO, T. A. EGEL, D. S. FÉLIX-GASTÉLUM, R. FRANCIS, D. M. KEBEDE, M. IVEY, M. L. LOUWS, F. J. LUO, L. MAYNARD, E. T. MILLER, S. A. NGUYEN, N. T. T. OSDAGHI, E. QUEZADO-DUVAL, A. M. ROACH, R. ROTONDO, F. RUHL, G. E. SHUTT, V. M. THUMMABENJAPONE, P. TRUEMAN, C. ROBERTS, P. D. JONES, J. B. VALLAD, G. E. GOSS, E. M.
Afiliación:	SUJAN TIMILSINA, UNIVERSIDADE DA FLORIDA FERNANDA IRUEGAS-BOCARDO MUSTAFA O. JIBRIN ANUJ SHARMA AASTHA SUBEDI AMANDEEP KAUR GERALD V. MINSAVAGE JOSE C. HUGUET-TAPIA JEANNIE KLEIN-GORDON PRAGYA ADHIKARI TIKA B. ADHIKARI GABRIELLA CIRVILLERI LAURA BELEN TAPIA DE LA BARRERA EDUARDO BERNAL TOM C. CRESWELL TIEN THI KIEU DOAN TERESA A. COUTINHO DANIEL S. EGEL RUBÉN FÉLIX-GASTÉLUM DAVID M. FRANCIS MISRAK KEBEDE MELANIE LEWIS IVEY FRANK J. LOUWS LAIXIN LUO ELIZABETH T. MAYNARD SALLY A. MILLER NGA THI THU NGUYEN EBRAHIM OSDAGHI ALICE M. QUEZADO-DUVAL, CNPH REBECCA ROACH FRANCESCA ROTONDO GAIL E. RUHL VOU M. SHUTT PETCHARAT THUMMABENJAPONE CHERYL TRUEMAN PAMELA D. ROBERTS JEFFREY B. JONES GARY E. VALLAD ERICA M. GOSS.
Año:	2025
Referencia:	PLOS Pathogens, v. 21, n. 4, e1013036, 2025.
Páginas:	28 p.
Descripción:	Emerging and re-emerging plant diseases continue to present multifarious threats to global food security. Considerable recent efforts are therefore being channeled towards understanding the nature of pathogen emergence, their spread and evolution. Xanthomonas euvesicatoria pv. perforans (Xep), one of the causal agents of bacterial spot of tomato, rapidly emerged and displaced other bacterial spot xanthomonads in many tomato production regions around the world. In less than three decades, it has become a dominant xanthomonad pathogen in tomato production systems across the world and presents a compelling example for understanding diversification of recently emerged bacterial plant pathogens. Although Xep has been continuously monitored in Florida since its discovery, the global population structure and evolution at the genome-scale is yet to be fully explored. The objectives of this work were to determine genetic diversity globally to ascertain if different tomato production regions contain genetically distinct Xep populations, to examine genetic relatedness of strains collected in tomato seed production areas in East Asia and other production regions, and to evaluate variation in type III secretion effectors, which are critical pathogenicity and virulence factors, in relationship to population structure. We used genome data from 270 strains from 13 countries for phylogenetic analysis and characterization of type III effector gene diversity among strains. Our results showed notable genetic diversity in the pathogen. We found genetically similar strains in distant tomato production regions, including seed production regions, and diversification over the past 100 years, which is consistent with intercontinental dissemination of the pathogen in hybrid tomato production chains. Evolution of the Xep pangenome, including the acquisition and loss of type III secreted effectors, is apparent within and among phylogenetic lineages. The apparent long-distance movement of the pathogen, together with variants that may not yet be widely distributed, poses risks of emergence of new variants in tomato production.
Thesagro:	Tomate Segurança Alimentar Mancha Bacteriana
NAL Thesaurus:	Bacterial diseases of plants
Palabras clave:	Xanthomonas euvesicatoria pv perforans
DOI:	org/10.1371/journal.ppat.1013036
Tipo de Material:	Artigo de periódico
Acceso:	openAccess
Aparece en las colecciones:	Artigo em periódico indexado (CNPH)