Title:	Metabolic engineering and process optimization for the production of ethylene glycol and glycolic acid by Komagataella phaffii.
Authors:	PACHECO, T. F. ANDRADE, T. M. G. de TORRES, N. A. BRANDALISE, E. F. DUARTE, L. T. ALMEIDA, J. R. M. de
Affiliation:	THALYTA FRAGA PACHECO, CNPAE; TÚLIO MARCOS GODOY DE ANDRADE, UNIVERSIDADE DE BRASÍLIA; NATHÁLIA ALINE TORRES, UNIVERSIDADE DE BRASÍLIA; EDUARDO FRANCO BRANDALISE, UNIVERSIDADE DE BRASÍLIA; LIVIA TEIXEIRA DUARTE, CNPAE; JOAO RICARDO MOREIRA DE ALMEIDA, CNPAE.
Date Issued:	2025
Citation:	In: CONGRESSO BRASILEIRO DE MICROBIOLOGIA, 33.; FOODMICRO LATINO, 1., 2025, Aracaju. Anais [...]. São Paulo: Sociedade Brasileira de Microbiologia, 2025.
Description:	This study aimed to develop a process for producing ethylene glycol (EG) and glycolic acid (GA) from biomass hydrolysates using robust strains of the yeast Komagataella phaffii. To achieve this, the recombinant strain K. phaffii JA122, capable of producing EG and GA, was constructed by expressing four enzymes (XDH, XD, ALDO, and either ALDR or ALDH).
Thesagro:	Microbiologia Industrial Biotecnologia
NAL Thesaurus:	Yeasts Metabolic engineering Xylose Ethylene glycol Glycolic acid
Keywords:	Levedura Engenharia metabólica Xilose Bioprodutos Komagataella phaffii
Notes:	ID do trabalho: 204/2667-0.
Type of Material:	Resumo em anais e proceedings
Access:	openAccess
Appears in Collections:	Resumo em anais de congresso (CNPAE)