Use este identificador para citar ou linkar para este item: http://www.alice.cnptia.embrapa.br/alice/handle/doc/1186207
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dc.contributor.authorSILVA, A. B. daeng
dc.contributor.authorPINTO, F. C. L.eng
dc.contributor.authorSILVEIRA, E. R.eng
dc.contributor.authorPAULO, T. de F.eng
dc.contributor.authorWILKE, D. V.eng
dc.contributor.authorFERREIRA, E. G.eng
dc.contributor.authorCOSTA-LOTUFOeng
dc.contributor.authorCANUTO, K. M.eng
dc.contributor.authorMARINHO FILHO, J. D. B.eng
dc.contributor.authorBARROS, A. B.eng
dc.contributor.authorNUZZO, G.eng
dc.contributor.authorFONTANA, A.eng
dc.contributor.authorMONTEIRO, R. K. V.eng
dc.date.accessioned2026-04-08T20:48:42Z-
dc.date.available2026-04-08T20:48:42Z-
dc.date.created2026-04-08
dc.date.issued2026
dc.identifier.citationJournal of Natural Products, 89, 304−312, 2026.
dc.identifier.urihttp://www.alice.cnptia.embrapa.br/alice/handle/doc/1186207-
dc.descriptionFive new rifamycin derivatives, named salinirifamy- cins A−E (1−5), were isolated from a Brazilian marine Salinispora arenicola (BRA-213) strain extract. The structures of the new rifamycins were elucidated using a combination of NMR, IR, UV, and MS spectroscopic techniques, quantum-chemical calculations (DFT-calculated 13 C NMR chemical shifts and DP4+ probability analysis), and comparison of experimental and calculated electronic circular dichroism (ECD) spectra. Compounds 1, 2, and 4 displayed antibacterial activity against Staphylococcus aureus and Enterococcus faecalis with MIC values ranging from 2.0 to 125.0 μg/ mL, whereas 5 exhibited an MIC of 0.02 μg/mL to S. aureus, similar to the positive control rifampicin (MIC 0.03 μg/mL).
dc.language.isoeng
dc.rightsopenAccess
dc.subjectSalinirifamicinas
dc.subjectSalinispora arenicola
dc.titleSalinirifamycins A−E: Rifamycin S Derivatives from the Brazilian Marine Actinomycete Salinispora arenicola.
dc.typeArtigo de periódico
dc.subject.nalthesaurusActinobacteria
riaa.ainfo.id1186207
riaa.ainfo.lastupdate2026-04-08
dc.identifier.doihttps://doi.org/10.1021/acs.jnatprod.5c01381
dc.contributor.institutionALISON BATISTA DA SILVA, UNIVERSIDADE FEDERAL DO CEARÁeng
dc.contributor.institutionFRANCISCO CHAGAS L. PINTO, UNIVERSIDADE FEDERAL DO CEARÁeng
dc.contributor.institutionEDILBERTO R. SILVEIRA, UNIVERSIDADE FEDERAL DO CEARÁeng
dc.contributor.institutionTERCIO DE FREITAS PAULO, UNIVERSIDADE FEDERAL DO CEARÁeng
dc.contributor.institutionDIEGO V. WILKE, UNIVERSIDADE FEDERAL DO CEARÁeng
dc.contributor.institutionELTHON G. FERREIRA, UNIVERSIDADE FEDERAL DO CEARÁeng
dc.contributor.institutionLETICIA V. COSTA-LOTUFO, UNIVERSIDADE DE SÃO PAULOeng
dc.contributor.institutionKIRLEY MARQUES CANUTO, CNPATeng
dc.contributor.institutionJOSÉ DELANO BARRETO MARINHO-FILHO, UNIVERSIDADE FEDERAL DO DELTA DO PARNAÍBAeng
dc.contributor.institutionAYSLAN B. BARROS, UNIVERSIDADE FEDERAL DO DELTA DO PARNAÍBAeng
dc.contributor.institutionGENOVEFFA NUZZO, ISTITUTO DI CHIMICA BIOMOLECOLARE, BIO-ORGANIC CHEMISTRY UNITeng
dc.contributor.institutionANGELO FONTANA, ISTITUTO DI CHIMICA BIOMOLECOLARE, BIO-ORGANIC CHEMISTRY UNITeng
dc.contributor.institutionNORBERTO KÁSSIO V. MONTEIRO, UNIVERSIDADE FEDERAL DO CEARÁ.eng
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