Título:	Regulatory harmonization needs for farm-to-fork bacteriophage applications in South American food systems.
Autor:	PARRA, B. BASTÍAS, R. HIGUERA, G. ROSALES, I. M. GALARCE, L. RIVERA, V. ALLEL, K. MARTINS, M. F. FLOREZ, M. J. V. JIMÉNEZ, J. N. ECHEVERRÍA, N. MARAMBIO, C. AGUAYO, D. GONZÁLEZ-ROCHA, G. VILLAMIL, A. FRESNO, M. RIVERA, D.
Afiliación:	BORIS PARRA, UNIVERSIDAD DE LAS AMÉRICAS ROBERTO BASTÍAS, PONTIFICIA UNIVERSIDAD CATÓLICA DE VALPARAÍSO GASTÓN HIGUERA, UNIVERSITY OF CHILE INÉS MARLENE ROSALES, PONTIFICIA UNIVERSIDAD CATÓLICA DE CHILE LORENA GALARCE, AGENCIA CHILENA PARA LA CALIDAD E INOCUIDAD ALIMENTARIA VÍCTOR RIVERA, AGENCIA CHILENA PARA LA CALIDAD E INOCUIDAD ALIMENTARIA KASIM ALLEL, PONTIFICIA UNIVERSIDAD CATÓLICA DE CHILE MARTA FONSECA MARTINS, CNPGL MARTHA JOSEFINA VIVES FLOREZ, UNIVERSIDAD DE LOS ANDES JUDY NATALIA JIMÉNEZ, UNIVERSITY OF ANTIOQUIA NATALIA ECHEVERRÍA, UNIVERSIDAD DE LA REPÚBLICA MONTEVIDEO CAROLINA MARAMBIO, DIVISIÓN PROTECCIÓN PECUARIA, SERVICIO AGRÍCOLA Y GANADERO DANIEL AGUAYO, UNIVERSIDAD ANDRÉS BELLO GERARDO GONZÁLEZ-ROCHA, UNIVERSIDAD DE CONCEPCIÓN AURA VILLAMIL, UNIVERSIDAD DE LAS AMÉRICAS MARCELA FRESNO, UNIVERSIDAD DE LAS AMÉRICAS DÁCIL RIVERA, UNIVERSIDAD DE LAS AMÉRICAS.
Año:	2026
Referencia:	Foods, v. 15, n. 11, 2031, 2026.
Descripción:	Bacteriophage-based products are gaining attention as effective tools to reduce harmful germs in food and combat antimicrobial resistance throughout the food production process. However, in South America, their use is still limited because of complicated regulations and inconsistent evidence requirements. This review aims to (i) explore the current scientific and technological landscape of using bacteriophages in South American food systems, (ii) identify main regulatory challenges that impact their classification, approval, and use, and (iii) highlight the need for consistent international guidelines, especially from Codex Alimentarius, to help safely and effectively incorporate phage-based products in food. Research on phage-based products is growing, but it is not consistent across different regions. There are more patents and advancements in biotechnology, but they are limited to certain areas. Although progress is being made, the regulatory frameworks are still unclear, especially when it comes to how these products are classified, labeled, and monitored for safety. To address these gaps, risk-based guidelines are needed. These should define product categories and claims, set safety standards, and include rules for tracking products and monitoring them after they hit the market. Creating a new Codex Alimentarius project on phage-based products could help establish global guidelines that promote safe use, reduce uncertainty in regulations, and improve trade in food markets around the world.
Thesagro:	Alimento Produção de Alimentos Regulamentação Diretriz
Palabras clave:	Bacteriófago
DOI:	https://doi.org/10.3390/foods15112031
Tipo de Material:	Artigo de periódico
Acceso:	openAccess
Aparece en las colecciones:	Artigo em periódico indexado (CNPGL)