Título:	Boosting growth, health, and productivity of Nile tilapia by supplementing Artemisia annua under tropical net cage farming conditions.
Autor:	SOARES, M. P. MARASCHI, A. C. ANGELIS, C. F. de QUEIROZ, S. C. do N. de JONSSON, C. M. CAMPOS, C. M. de FERNANDES, M. N. LEITE, C. A. C. RANTIN, F. T. SAMPAIO, F. G.
Afiliación:	MICHELLY PEREIRA SOARES, UNIVERSIDADE FEDERAL DE SÃO CARLOS; ANIELI CRISTINA MARASCHI, UNIVERSIDADE FEDERAL DE SÃO CARLOS; CAROLINA FERNANDES DE ANGELIS, UNIVERSIDADE FEDERAL DE SÃO CARLOS; SONIA CLAUDIA DO NASCIMENTO DE QUEIROZ, CNPMA; CLAUDIO MARTIN JONSSON, CNPMA; CRISTIANE MELDAU DE CAMPOS, UNIVERSIDADE ESTADUAL DE MATO GROSSO DO SUL; MARISA NARCISO FERNANDES, UNIVERSIDADE FEDERAL DE SÃO CARLOS; CLÉO ALCANTARA COSTA LEITE, UNIVERSIDADE FEDERAL DE SÃO CARLOS; FRANCISCO TADEU RANTIN, UNIVERSIDADE FEDERAL DE SÃO CARLOS; FERNANDA GARCIA SAMPAIO, CNPMA.
Año:	2026
Referencia:	Aquaculture Reports, v. 48, article 103514, 2026., Elsevier BV, 2026
Descripción:	Abstract: The rapid global expansion of aquaculture demands innovative strategies to enhance productivity while safeguarding fish health under intensive rearing conditions. This study investigated the effects of dietary supplementation with an alcoholic extract of Artemisia annua (ae-Aa) on growth performance, physiological stress, immune responses, oxidative status, and tissue morphology of Nile tilapia (Oreochromis niloticus) cultured in a high-density net-cage system. A 2 × 2 factorial was applied, including two dietary treatments (supplemented, S; non-supplemented, NS) and two feeding periods (30 and 60 days), yielding four experimental groups (S-30, NS-30, S-60, NS-60). Compared with their respective controls, ae-Aa supplementation significantly enhanced survival and growth at both time points (P < 0.05), evidenced by greater weight gain and protein efficiency ratio and a reduced feed conversion ratio. Supplemented fish also showed increased intestinal villus thickness and hepatosomatic index (P < 0.05). Plasma cortisol concentrations were significantly lower in supplemented groups at both sampling periods (P < 0.05). Moreover, ae-Aa supplementation stimulated innate immune responses, reflected by elevated lysozyme activity, plasma protein level, and leukocyte respiratory burst (P < 0.05). Oxidative stress was notably mitigated in supplemented fish (P < 0.05), with reduced lipid peroxidation, enhanced catalase, glutathione peroxidase, and glutathione S-transferase activities, and decreased DNA damage observed at 60 days. In conclusion, dietary ae-Aa supplementation improved growth performance, immune competence, antioxidant capacity, and tissue integrity while alleviating physiological stress in Nile tilapia, supporting its application as a sustainable plant-based feed additive for intensive aquaculture systems.
Thesagro:	Artemísia Artemisia Annua Tilápia Nilótica Estimulante de Crescimento Animal Produção Pesqueira Produtividade Antioxidante Peroxidase Aquicultura Imunidade
NAL Thesaurus:	Tilapia (common name) Immune response Feed conversion
Palabras clave:	Phytogenic feed additives Stress regulation Immune enhancement Antioxidant defense Sustainable aquaculture Intestinal morphology
ISSN:	2352-5134
DOI:	https://doi.org/10.1016/j.aqrep.2026.103514
Tipo de Material:	Artigo de periódico
Acceso:	openAccess
Aparece en las colecciones:	Artigo em periódico indexado (CNPMA)