Title:	Association of GH and IGF-1 polymorphisms with growth traits in a synthetic beef cattle breed.
Authors:	PEREIRA, A. P. ALENCAR, M. M. de OLIVEIRA, H. N. de REGITANO, L. C. de A.
Affiliation:	ANDRÉA POZZI PEREIRA, UFSCAR; MAURICIO MELLO DE ALENCAR, CPPSE; HENRIQUE NUNES DE OLIVEIRA, UNESP; LUCIANA CORREIA DE ALMEIDA REGITANO, CPPSE.
Date Issued:	2005
Citation:	Genetics and Molecular Biology, v. 28, n. 2, p. 230-236, 2005.
Description:	The Canchim beef cattle (5/8 Charolais + 3/8 Zebu) has been selected for meat production in Brazil since late 1950. In the present work the effects of growth hormone ( GH) and insulin-like growth factor 1 ( IGF-1) polymorphisms were investigated in 688 animals born between 1998 and 2000. These animals belonged to two genetic groups, i.e., traditional and new lineages. Genotype effects on expected breeding values for birth weight (BW), weaning weight (WW) and yearling weight (YW) were investigated by the least square method. Significant effects were found for GH genotype on YW (p = 0.05), with positive effects associated with the LV (leucine/valine) genotype. For IGF-1 genotypes, significant effects were found on BW (p = 0.01) and YW (p = 0.01). Average substitution effects for IGF-1 alleles estimated by regression analysis suggested a positive effect of the IGF-1225 bp allele on BW and of the 229 bp allele on YW.
NAL Thesaurus:	beef cattle genotype
Keywords:	Genetic association Growth hormone Insulin like growth factor 1
DOI:	https://doi.org/10.1590/S1415-47572005000200009
Type of Material:	Artigo de periódico
Access:	openAccess
Appears in Collections:	Artigo em periódico indexado (CPPSE)