Title:	Action of sisal (Agave sisalana, Perrine) extract in the in vitro development of sheep and goat gastrointestinal nematodes.
Authors:	SILVEIRA, R. X. CHAGAS, A. C. de S. BOTURA, M. B. BATITINHA, M. J. M. KATIKI, L. M. CARVALHO, C. O. BEVELAQUA, C. M. L. BRANCO, A. MACHADO, E. A. A. BORGES, S. L. ALMEIDA, M. A. O.
Affiliation:	ROBERTA X. SILVEIRA, UNIVERSIDADE FEDERAL DA BAHIA; ANA CAROLINA DE SOUZA CHAGAS, CPPSE; MARIANA B. BOTURA, UNIVERSIDADE FEDERAL DA BAHIA; MARIA J. M. BATATINHA, UNIVERSIDADE FEDERAL DA BAHIA; LUCIANA M. KATIKI, INSTITUTO DE ZOOTECNIA; CAMILA O. CARVALHO, LABORATÓRIO DE SANIDADE ANIMAL; CLAUDIA M. L. BEVILAQUA, UNIVERSIDADE ESTADUAL DE CEARÁ; ALEXSANDRO BRANCO, UNIVERSIDADE ESTADUAL DE FEIRA DE SANTANA; ELANE A. A. MACHADO, UNIVERSIDADE FEDERAL DA BAHIA; SIMONE L. BORGES, UNIVERSIDADE FEDERAL DA BAHIA; MARIA A. O. ALMEIDA, UNIVERSIDADE FEDERAL DA BAHIA.
Date Issued:	2012
Citation:	Experimental parasitology, v. 131, n. 2, p. 162-168, jun. 2012.
Description:	Active compounds from Agave sisalana with antiparasitic action against gastrointestinal nematodes (GINs) could be an alternative to diversify the range of parasite management methods in the livestock sector. The objective of this study was to evaluate the in vitro action of A. sisalana extract on the development of sheep and goat GINs. The extract, obtained from shredded sisal leaves, was utilized at various concentrations in the egg hatch test (EHT), larval development test (LDT), larval feeding inhibition test (LFIT) and adult motility test (AMT). The LC50 and LC95 in the EHT were 6.90 and 24.79 mg/mL, in the LDT were 0.041 and 0.067 mg/mL and in the LFIT were 0.053 and 0.24 mg/mL, respectively, showing a dose-dependent relationship. The development and feeding inhibition on L1 were both 100% at a dose of 0.12 mg/mL. In the AMT there was 100% inhibition at 75 mg/mL after 24 h of exposure. The extract of A. sisalana therefore demonstrated significant action on L1 at 0.12 mg/mL. So, if part of the A. sisalana extract passes through the animal?s gastrointestinal system, this material can have a significant effect on the parasites in the feces. This is an interesting a approach because it can drastically reduce the pasture contamination as well as the infection of herds.
Thesagro:	Agavaceae Haemonchus Contortus
Keywords:	Phytomedicine Pasture contamination Small ruminat
DOI:	https://doi.org/10.1016/j.exppara.2012.03.018
Type of Material:	Artigo de periódico
Access:	openAccess
Appears in Collections:	Artigo em periódico indexado (CPPSE)