Title:	Molecular evolution of the ? -casp family suggests functional homology with rag1/rag2 proteins: a new model for dna interstrand crosslink repair, nonhomologous end-joining and v(d)j recombination in yeast and vertebrates.
Authors:	BONATTO, D. REVERS, L. F. BRENDEL, MARTIN PÊGAS, J. A.
Affiliation:	DIEGO BONATTO, UNIVERSIDADE FEDERAL DO RIO GRANDE DO SUL; LUIS FERNANDO REVERS, CNPUV; MARTIN BRENDEL, UNIVERSIDADE FEDERAL DO RIO GRANDE DO SUL; JOÃO ANTONIO PÊGAS, UNIVERSIDADE FEDERAL DORIO GRANDE DO SUL.
Date Issued:	2003
Citation:	CONGRESSO NACIONAL DE GENÉTICA, 49., 2003, Águas de Lindóia. A dupla hélice do DNA: anais. Águas de Lindóia: Sociedade Brasileira de Genética, 2003. gm011.
Pages:	1 P.
Description:	Non-homologous end-joining (NHEJ) and V(D)J recombination are importan t pathways for DNA double strand break repair (DSBR) and for generation of immunological diversity in lymphocytes, respectively. The main feature of both pathways is that they share common protein complexes that recruit NHEJ- or V(D)J-specific proteins. Proteins of the ?-CASP family, functionally related to DNA or RNA metabolism, are necessary for NHEJ and DNA interstrand cross-link repair.
Thesagro:	DNA
NAL Thesaurus:	Phylogeny
Keywords:	NHEJ Non-homologous end-joining (NHEJ) Double strand break repair (DSBR) Repair
Type of Material:	Resumo em anais e proceedings
Access:	openAccess
Appears in Collections:	Resumo em anais de congresso (CNPUV)