Título:	Dynamics of catalysis and inhibition in oligopeptidases: natural peptide structures as promising antihypertensive agents.
Autor:	FERNANDEZ, J. H. RIOLI, V. NESHICH, G. FERRO, E. S. PORTARO, F. C. CAMARGO, A. C. M.
Afiliación:	JORGE H. FERNANDEZ, Instituto Butantan; VANESSA RIOLI, Instituto Butantan; GORAN NESHICH, CNPTIA; EMMER S. FERRO, USP; FERNANDA C. PORTARO, Instituto Butantan; ANTONIO C. M. CAMARGO, Instituto Butantan.
Año:	2006
Referencia:	In: ANNUAL INTERNATIONAL CONFERENCE ON INTELLIGENT SYSTEMS FOR MOLECULAR BIOLOGY, 14.; ANNUAL AB3C CONFERENCE, 2., 2006, Fortaleza. Conference Program... Fortaleza: ISCB, 2006.
Páginas:	Não paginado.
Descripción:	Short Abstract: Molecular modeling, combined with docking and molecular dynamics experiments was used to study the dynamics of catalysis/inhibition in ?druggable? human Oligopeptidases. The dynamics of ligand recognition and structural determinants for selective inhibition of these enzymes lead us to propose more selective oligopeptidase inhibitors with improved stability and pharmacological profile.
Thesagro:	Biologia molecular Genoma Proteína Análise Comparativa
NAL Thesaurus:	Molecular biology Genome Proteins
Notas:	ISMB, X-MEETING 2006. Poster E-8.
Tipo de Material:	Resumo em anais e proceedings
Acceso:	openAccess
Aparece en las colecciones:	Resumo em anais de congresso (CNPTIA)