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|Research center of Embrapa/Collection:||Embrapa Pecuária Sudeste - Artigo em periódico indexado (ALICE)|
|Type of Material:||Artigo em periódico indexado (ALICE)|
|Authors:||SOUZA, M. M. de|
ZERLOTINI NETO, A.
TIZIOTO, P. C.
TAYLOR, J. F.
ROCHA, M. I. P.
DINIZ, W. J. S.
COUTINHO, L. L.
REGITANO, L. C. de A.
|Additional Information:||Marcela M. de Souza, UFSCar; ADHEMAR ZERLOTINI NETO, CNPTIA; Ludwig Geistlinger, FAPESP; Polyana C. Tizioto, NGS Genomic Solution; Jeremy F. Taylor, University of Missouri; Marina I. P. Rocha, UFSCar; Wellison J. S. Diniz, UFSCar; Luiz L. Coutinho, USP; LUCIANA CORREIA DE ALMEIDA REGITANO, CPPSE.|
|Title:||A comprehensive manually-curated compendium of bovine transcription factors.|
|Publisher:||Scientific Reports, v.8, n.13747, p.1-12, jan. 2018.|
Gene expression in cattle
|Description:||Transcription factors (TFs) are pivotal regulatory proteins that control gene expression in a contextdependent and tissue-specific manner. In contrast to human, where comprehensive curated TF collections exist, bovine TFs are only rudimentary recorded and characterized. In this article, we present a manually-curated compendium of 865 sequence-specific DNA-binding bovines TFs, which we analyzed for domain family distribution, evolutionary conservation, and tissue-specific expression. In addition, we provide a list of putative transcription cofactors derived from known interactions with the identified TFs. Since there is a general lack of knowledge concerning the regulation of gene expression in cattle, the curated list of TF should provide a basis for an improved comprehension of regulatory mechanisms that are specific to the species.|
|NAL Thesaurus:||Gene expression regulation|
|Appears in Collections:||Artigo em periódico indexado (CPPSE)|
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