Título:	Transcriptomic analysis identifies differentially expressed genes related to lipid metabolism in extreme animals for GEBV for iron content in the muscle Nelore steers.
Autor:	DINIZ, W. J. DA S. TIZIOTO, P. C. COUTINHO, L. L. CESAR, A. S. M. GROMBONI, C. F. NOGUEIRA, A. R. de A. REGITANO, L. C. de A.
Afiliación:	WELLISON JARLES DA SILVA DINIZ, Federal University of São Carlos; POLYANA CRISTINE TIZIOTO; LUIZ LEHMANN COUTINHO, University of São Paulo; ALINE SILVA MELLO CESAR, University of São Paulo; CAIO FERNANDO GROMBONI, Bahia Federal Institute of Education; ANA RITA DE ARAUJO NOGUEIRA, CPPSE; LUCIANA CORREIA DE ALMEIDA REGITANO, CPPSE.
Año:	2015
Referencia:	In: REUNIÃO ANUAL DA SOCIEDADE BRASILEIRA DE ZOOTECNIA, 52., Belo Horizonte, 2015. Anais... Belo Horizonte: SBZ, 2015.
Descripción:	Iron is essential to several biological processes, such as oxygen transport and lipid metabolism. In this study, the RNA sequencing technology (RNAseq) was adopted to identify differentially expressed genes (DE) and metabolic pathways, as well as its relationship with meat quality parameters influenced by the variation in iron content (IC) in muscle. Samples of Longissimus dorsi (LD) muscle from Nelore cattle (n = 8), extreme genomic estimated breeding value (GEBV) for IC (four samples with high (HIL) and four low (LIL) GEBV) were used. Data analysis by Tuxedo Suite identified 49 annotated genes DE between the groups. The functional enrichment analysis identified important metabolic pathways associated with lipid metabolism, like stearate biosynthesis, fatty acid biosynthesis and palmitate biosynthesis, which participate in the gene FASN, FABP4, SLC27A6 and THRSP. These results suggest biologic pathways influenced by iron and contribute information for the understanding of their participation in the process that affects muscle physiology in cattle.
NAL Thesaurus:	Fatty acids Gene expression
Palabras clave:	Iron metabolism Longissimus dorsi
Tipo de Material:	Artigo em anais e proceedings
Acceso:	openAccess
Aparece en las colecciones:	Artigo em anais de congresso (CPPSE)