Título:	Antitumor, anti-inflammatory, and antioxidant activities of anthocyanins from food and isolated sources: Methodological insights and interactions with the intestinal microbiota.
Autoria:	SANTOS, E. de F. dos SABINO, Y. N. V. MONTENEGRO, E. N. FARIA, C. A. ALMEIDA, T, C. de GAMEIRO, J. LUQUETTI, S. C. P. D. MACHADO, A. B. F. MACHADO, J. C.
Afiliação:	ERIKA DE FATIMA DOS SANTOS, UNIVERSIDADE FEDERAL DE JUIZ DE FORA YASMIN NEVES VIEIRA SABINO, QUEEN’S UNIVERSITY BELFAST ELISA NASSIF MONTENEGRO, UNIVERSIDADE FEDERAL DE JUIZ DE FORA CINTHIA ALVIM FARIA, UNIVERSIDADE FEDERAL DE JUIZ DE FORA THAÍS COSTA DE ALMEIDA, UNIVERSIDADE FEDERAL DE JUIZ DE FORA JACY GAMEIRO, UNIVERSIDADE FEDERAL DE JUIZ DE FORA SHEILA CRISTINA POTENTE DUTRA LUQUETTI, UNIVERSIDADE FEDERAL DE JUIZ DE FORA ALESSANDRA BARBOSA FERREIRA MACHADO, UNIVERSIDADE FEDERAL DE JUIZ DE FORA JUAREZ CAMPOLINA MACHADO, CNPGL.
Ano de publicação:	2025
Referência:	Journal of Functional Foods, v. 134, 107026, 2025.
Conteúdo:	Anthocyanins are secondary metabolites found in plants, commonly present in fruits such as strawberries, grapes, and blueberries. They act as antioxidants, protecting plant cells from oxidative damage, and are known for their potential role in chronic disease prevention. In studies, anthocyanins have been investigated both in food matrices and in isolated forms. They neutralize free radicals, which can damage cells, and reduce inflammation by downregulating pro-inflammatory cytokines involved in chronic diseases. Additionally, they have shown potential in modulating tumor cell proliferation, making them valuable for human health. This review explores the antioxidant, anti-inflammatory, and antitumor activities of anthocyanins, highlighting the methods used to assess these properties. Moreover, it discusses their interaction with the gut microbiota, which enhances anthocyanin biological effect through the production of short-chain fatty acids and phenolic metabolites derived from microbial metabolism. The review also addresses the challenges and future perspectives for the industrialscale application of anthocyanins.
Thesagro:	Microbiologia Intestino Saúde Antioxidante Antiinflamatório
NAL Thesaurus:	Anthocyanins Bioavailability Human health
Digital Object Identifier:	https://doi.org/10.1016/j.jff.2025.107026
Tipo do material:	Artigo de periódico
Acesso:	openAccess
Aparece nas coleções:	Artigo em periódico indexado (CNPGL)