Title:	The role of the pentose phosphate pathway on reproductive functions.
Authors:	BRAGA, J. V. CAMARGO, J. de MARQUES, M. G. MONDADORI, R. G. LUCIA JUNIOR, T.
Affiliation:	JOSÉ VICTOR BRAGA, UNIVERSIDADE FEDERAL DE PELOTAS; JANINE DE CAMARGO, UNIVERSIDADE DE PASSO FUNDO; MARIANA GROKE MARQUES, CNPSA; RAFAEL GIANELLA MONDADORI, UNIVERSIDADE FEDERAL DE PELOTAS; THOMAZ LUCIA JUNIOR, UNIVERSIDADE FEDERAL DE PELOTAS.
Date Issued:	2025
Citation:	Animal Reproduction, v. 22, n. 4, ed. e20240130, 2025.
Description:	The application of assisted reproductive techniques (ART) in both farm animals and humans has faced challenges since its inception. Advances in this field have largely depended on a deeper understanding of the metabolic requirements and molecular dynamics of sperm, oocytes, and embryonic development. Glucose, for instance, is commonly utilized as an energy source in in vitro procedures. The pentose phosphate pathway (PPP), a pathway parallel to glycolysis, plays a key role in redox regulation via NADPH generation and ribose biosynthesis. This review highlights the role of the PPP in reproductive cells and discusses its potential implications for ART procedures.
Thesagro:	Metabolismo Animal Espermatogênese
NAL Thesaurus:	Metabolism Spermatogenesis
Keywords:	Desenvolvimento embrionario Embryo development Oocyte maturation
DOI:	https://doi.org/10.1590/1984-3143-AR2024-0130
Type of Material:	Artigo de periódico
Access:	openAccess
Appears in Collections:	Artigo em periódico indexado (CNPSA)