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Título: The role of the pentose phosphate pathway on reproductive functions.
Autor: BRAGA, J. V.
CAMARGO, J. de
MARQUES, M. G.
MONDADORI, R. G.
LUCIA JUNIOR, T.
Afiliación: JOSÉ VICTOR BRAGA, UNIVERSIDADE FEDERAL DE PELOTAS; JANINE DE CAMARGO, UNIVERSIDADE DE PASSO FUNDO; MARIANA GROKE MARQUES, CNPSA; RAFAEL GIANELLA MONDADORI, UNIVERSIDADE FEDERAL DE PELOTAS; THOMAZ LUCIA JUNIOR, UNIVERSIDADE FEDERAL DE PELOTAS.
Año: 2025
Referencia: Animal Reproduction, v. 22, n. 4, ed. e20240130, 2025.
Descripción: The application of assisted reproductive techniques (ART) in both farm animals and humans has faced challenges since its inception. Advances in this field have largely depended on a deeper understanding of the metabolic requirements and molecular dynamics of sperm, oocytes, and embryonic development. Glucose, for instance, is commonly utilized as an energy source in in vitro procedures. The pentose phosphate pathway (PPP), a pathway parallel to glycolysis, plays a key role in redox regulation via NADPH generation and ribose biosynthesis. This review highlights the role of the PPP in reproductive cells and discusses its potential implications for ART procedures.
Thesagro: Metabolismo Animal
Espermatogênese
NAL Thesaurus: Metabolism
Spermatogenesis
Palabras clave: Desenvolvimento embrionario
Embryo development
Oocyte maturation
DOI: https://doi.org/10.1590/1984-3143-AR2024-0130
Tipo de Material: Artigo de periódico
Acceso: openAccess
Aparece en las colecciones:Artigo em periódico indexado (CNPSA)

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