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http://www.alice.cnptia.embrapa.br/alice/handle/doc/1187033Registro completo de metadados
| Campo DC | Valor | Idioma |
|---|---|---|
| dc.contributor.author | SORIGOTTI, A. R. | |
| dc.contributor.author | PASCHOALIN, R. T. | |
| dc.contributor.author | SILVA, R. R. da | |
| dc.contributor.author | FERNANDES, R. F. | |
| dc.contributor.author | BARUD, H. da S. | |
| dc.contributor.author | RIBEIRO, S. J. L. | |
| dc.contributor.author | OLIVEIRA JR, O. N. | |
| dc.contributor.author | OTONI, C. G. | |
| dc.contributor.author | MATTOSO, L. H. C. | |
| dc.date.accessioned | 2026-05-22T13:54:45Z | - |
| dc.date.available | 2026-05-22T13:54:45Z | - |
| dc.date.created | 2026-05-22 | |
| dc.date.issued | 2026 | |
| dc.identifier.citation | ACS Applied Bio Materials, v. 9, 2026. | |
| dc.identifier.uri | http://www.alice.cnptia.embrapa.br/alice/handle/doc/1187033 | - |
| dc.description | Thedevelopmentofbioinspirednanofibrousscaffoldswithadjustablefunctionsisessential forarangeofapplications, fromtissueengineeringtosustainablematerialsthatexploitthehierarchicalarchitecturesofBombyxmorisilks.Inthiswork,wereport theproductionoforganic−inorganicnanofibersbyincorporatingtheorganosilane(3-aminopropyl)triethoxysilane(APTES)intosilk fibroinusingthesolutionblowspinning(SB-spinning)technique.TheincorporationofAPTESaimstomodulatesolutionrheological properties,promoteconformational transitiontoβ-sheet-richstructures,andincreasethethermal stabilityof theresultingnanofiber, makingthemmoresuitableforbiomedicalapplications.SilkfibroinwasisolatedfromB.moricocoons,dissolvedinaternaryCaCl2/ EtOH/H2Osolution,andhybridizedwithAPTESbeforefiberproduction.Theresultingnanofibersdisplayedsmooth,uniformmor phologies andnanoscalediameters, confirming theeffectivenessof SB-spinning for creatinghybridsystems.Rheological analyses showedthataddingAPTESreducedviscosityandenhancedtheprocessabilityoffibroinsolutions.SpectroscopicandX-raydiffraction datarevealedanincreasedβ-sheetcontentandcrystallinityinthehybridfibers,whilethermogravimetricanalysisindicatedimproved thermal stability.Overall, theseresultsdemonstrate that incorporatingAPTESeffectivelyalters thephysicochemical andstructural propertiesofsilkfibroin,enablingtheproductionofpromisingnanofibrousscaffoldsforbiomedicalapplications.Thisstudythusintro ducesanapproachtoengineeringorganic−inorganichybridbiomaterialsviaascalable, low-costspinningprocess. KEYWORDS: biopolymers, solutionblowspinning,APTES,hybridnanofibers, tissueengineering | |
| dc.language.iso | eng | |
| dc.rights | openAccess | |
| dc.subject | FIbroin nanofibers | |
| dc.subject | APTES | |
| dc.title | Bioinspired Engineering ofBombyx mori Silk Fibroin:Solution Blow-Spun Nanofibers Hybridized with (3-Aminopropyl) triethoxysilane. | |
| dc.type | Artigo de periódico | |
| dc.format.extent2 | 4170−4181 | |
| riaa.ainfo.id | 1187033 | |
| riaa.ainfo.lastupdate | 2026-05-22 | |
| dc.identifier.doi | https://doi.org/10.1021/acsabm.6c00155 | |
| dc.contributor.institution | UNIVERSITY OF SÃO PAULO (USP); NANOSCIENTIFCA SCANDINAVIAN AB, GOTHENBURG 41 390, SWEDEN; CENTRO UNIVERSITÁRIO DE ARARAQUARA; INSTITUTE OF CHEMISTRY, SÃO PAULO STATE UNIVERSITY (UNESP); SÃO CARLOS INSTITUTE OF PHYSICS (IFSC), UNIVERSITY OF SÃO PAULO (USP); FEDERAL UNIVERSITY OF SÃO CARLOS (UFSCAR); LUIZ HENRIQUE CAPPARELLI MATTOSO, CNPDIA. | |
| Aparece nas coleções: | Artigo em periódico indexado (CNPDIA)  | |
Arquivos associados a este item:
| Arquivo | Descrição | Tamanho | Formato | |
|---|---|---|---|---|
| Bioinspired-Engineering-of-Bombyx-mori-Silk-Fibroin-Solution.pdf | 5,08 MB | Adobe PDF |  Visualizar/Abrir |
