Title:	Cellulose nanofibrils/AgNP nanostructured coating on smart packaging for indication of H2O2 in milk.
Authors:	TEODORO. K. B. R. BONDANCIA, T. J. SANFELICE, R. C. BALOGH, D. T. DENNEULIN, A. CORREA, D. S. MATTOSO, L. H. C. BRAS, J.
Affiliation:	UNIVERSITY GRENOBLE ALPES, CNRS, GRENOBLE INP, LGP2, 38000, GRENOBLE, FRANCE UNIVERSITY GRENOBLE ALPES, CNRS, GRENOBLE INP, LGP2, 38000, GRENOBLE, FRANCE FEDERAL UNIVERSITY OF ALFENAS (UNIFAL-MG), BRAZIL UNIVERSITY OF SAO PAULO, SAO CARLOS, SP, BRAZIL UNIVERSITY GRENOBLE ALPES, CNRS, GRENOBLE INP, LGP2, 38000, GRENOBLE, FRANCE DANIEL SOUZA CORREA, CNPDIA LUIZ HENRIQUE CAPPARELLI MATTOSO, CNPDIA UNIVERSITY GRENOBLE ALPES, CNRS, GRENOBLE INP, LGP2, 38000, GRENOBLE, FRANCE.
Date Issued:	2026
Citation:	International Journal of Biological Macromolecules, v. 367, 152613, 2026.
Pages:	12 p.
Description:	Colorimetric sensors offer user-friendly means of analysis, and do not require wired connections or antennas. These attributes make them suitable for integration into intelligent packaging systems, which enables real-time monitoring of product quality throughout the production and logistics chain, extending to the end consumer. Here we developed colorimetric sensors for detecting H 2 O 2 adulteration in milk with a simple and cost-effective approach. Specifically, the sensor was manufactured using paper and can be adapted for use as labels or seals for commercial packaging. A nanohybrid formulation comprising TEMPO-oxidized cellulose nanofibrils and silver nanoparticles (AgNP) was used to modify the paper surface via bar coating technique. Nanocellulose acted as a stabilizer and nucleating site for the synthesis of AgNP and facilitated the homogeneous deposition of the nanohybrid formulation onto the paper. Applying CNF/AgNP improved the paper's roughness and porosity, resulting in homogeneous samples with stable optical properties. The developed platform demonstrated visible bleaching in the presence of H 2 O μ 2 within a concentration range of 100 μ M to 1 mM, with a detection limit of 74 M, good selectivity against common interfering molecules found in milk, and suitable response in recovery tests using whole, semi-skimmed and skimmed milk, demonstrating its potential for real samples analysis.
Keywords:	Colorimetric sensor Coating
ISSN:	0141-8130
DOI:	https://doi.org/10.1016/j.ijbiomac.2026.152613
Type of Material:	Artigo de periódico
Access:	openAccess
Appears in Collections:	Artigo em periódico indexado (CNPDIA)