Title:	Effects of quantitative trait loci on iron content of bovine longissimus dorsi muscle.
Authors:	TIZIOTO, P. C. TAYLOR, J. F. DECKER, J. E. GROMBONI, C. F. MUDADU, M. de A. SCHNABEL, R. D. COUTINHO, L. L. MOURÃO, G. B. NASSU, R. T. DONATONI, F. A. B. THOLON, P. SONSTEGARD, T. S. ALENCAR, M. M. de TULLIO, R. R. REECY, J. M. NOGUEIRA, A. R. de A. REGITANO, L. C. de A.
Affiliation:	POLYANA C. TIZIOTO, UFSCar/SÃO CARLOS, SP J. F. TAYLOR, DIVISION OF ANIMAL SCIENCES, UNIVERSITY OF MISSOURI J. E. DECKER, DIVISION OF ANIMAL SCIENCES, UNIVERSITY OF MISSOURI C. F. GROMOBONI, USP-ESALQ / PIRACICABA MAURICIO DE ALVARENGA MUDADU, CPPSE R. D. SCHNABEL, DIVISION OF ANIMAL SCIENCES, UNIVERSITY OF MISSOURI L. L. COUTINHO, USP-ESALQ / PIRACICABA G. B. MOURÃO, USP-ESALQ / PIRACICABA RENATA TIEKO NASSU, CPPSE FLAVIA ALINE BRESSANI DONATONI, CPPSE PATRICIA THOLON, CPPSE T. S. SONSTEGARD, AGRICULTURAL RESEARCH SERVICE (USDA) MAURICIO MELLO DE ALENCAR, CPPSE RYMER RAMIZ TULLIO, CPPSE J. M. REECY, AGRICULTURAL RESEARCH SERVICE / IOWA ANA RITA DE ARAUJO NOGUEIRA, CPPSE LUCIANA CORREIA DE ALMEIDA REGITANO, CPPSE.
Date Issued:	2014
Citation:	In: WORLD CONGRESS OF GENETICS APPLIED TO LIVESTOK PRODUCTION, 10., 2014, Vancouver. Proceedings... Vancouver: American Society of Animal Science, 2014.
Pages:	3 p.
Description:	Beef cattle require dietary minerals to maintain their health, production and reproduction. Concentration of iron in bovine tissues is at least partially genetically determined. We genotyped 373 Nelore steers from 34 half-sib families with the Illumina BovineHD BeadChip. Genome-wide association analysis was performed for iron content of the longissimus dorsi muscle using a Bayesian approach. A large-effect QTL which explained 6.53% of the additive genetic variance in iron amount was detected at 72 Mb on BTA12. The candidate gene lists generated for all detected QTL were enriched for genes involved in signal transduction, signaling pathway, integral to membrane, intrinsic to membrane, regulation of transcription and metal ion binding. Our findings provide the first step towards the implementation of genomic selection for iron content in Nelore beef cattle, however validation in other populations will be required to estimate the accuracy of molecular estimates of breeding values
Thesagro:	Bos Indicus
Keywords:	Fe GWAS
Type of Material:	Artigo em anais e proceedings
Access:	openAccess
Appears in Collections:	Artigo em anais de congresso (CPPSE)