Title:	Serum Metabolomic Profiling in Healthy Dogs Supplemented with Increasing Levels of Purified Beta-1,3/1,6-Glucans.
Authors:	MARCHI, P. H. PRÍNCIPE, L. A. TRINDADE, F. S. SANTOS, L. D. dos FINARDI, G. L. F. FERNANDES, E. L. PUTAROV, T. C. RIBEIRO, G. H. COLNAGO, L. A. BALIEIRO, J. C. de C. VENDRAMINI, T. H. A.
Affiliation:	UNIVERSITY OF SAO PAULO; UNIVERSITY OF SAO PAULO; UNIVERSITY OF SAO PAULO; UNIVERSITY OF SAO PAULO; UNIVERSITY OF SAO PAULO; UNIVERSITY OF SAO PAULO; BIORIGIN (AÇUCAREIRA QUATÁ S.A.); LUIZ ALBERTO COLNAGO, CNPDIA; UNIVERSITY OF SAO PAULO; UNIVERSITY OF SAO PAULO.
Date Issued:	2025
Citation:	Animals, v. 15, 1211, 2025.
Pages:	16 p.
Description:	Simple Summary: Diet plays a crucial role in the health of dogs, and researchers are constantly exploring ways to improve nutrition through dietary supplements. This study investigated how beta-1,3/1,6-glucans, a nutraceutical known for its potential immune and gut health benefits, affect the metabolism of healthy dogs. Eight dogs participated in a controlled experiment using a double Latin square design, ensuring that each animal received all diet treatments in a balanced way. This study lasted a total of 140 days, divided into four experimental periods of 35 days each. The dogs were fed diets with different amounts of beta-glucans (0.0%, 0.07%, 0.14%, and 0.28%), and blood samples were collected at the end of each period to analyze metabolic changes. The results showed that certain levels of beta-glucans (0.07% and 0.14%) had a greater impact on metabolism, particularly in pathways related to amino acids and energy production. These findings help us to better understand how this supplement interacts with a dog’s body and could contribute to the development of more tailored and beneficial diets for pets. Further research is needed to explore the long-term effects and practical applications of beta-glucan supplementation in pet nutrition
Keywords:	Canine Nutraceuticals Omics sciences Supplementation
DOI:	https://doi.org/10.3390/ani15091211
Type of Material:	Artigo de periódico
Access:	openAccess
Appears in Collections:	Artigo em periódico indexado (CNPDIA)