Please use this identifier to cite or link to this item: http://www.alice.cnptia.embrapa.br/alice/handle/doc/1102174
Research center of Embrapa/Collection: Embrapa Informática Agropecuária - Artigo em periódico indexado (ALICE)
Date Issued: 2018
Type of Material: Artigo em periódico indexado (ALICE)
Authors: SOUZA, M. M. de
ZERLOTINI NETO, A.
GEISTLINGER, L.
TIZIOTO, P. C.
TAYLOR, J. F.
ROCHA, M. I. P.
DINIZ, W. J. S.
COUTINHO, L. L.
REGITANO, L. C. de A.
Additional Information: MARCELA M. DE SOUZA, UFSCar; ADHEMAR ZERLOTINI NETO, CNPTIA; LUDWIG GEISTLINGER, CPPSE; POLYANA C. TIZIOTO, NGS Genomic Solution; JEREMY F. TAYLOR, University of Missouri; MARINA I. P. ROCHA, UFSCar; WELLISON J. S. DINIZ, UFSCar; LUIZ L. COUTINHO, USP; LUCIANA CORREIA DE ALMEIDA REGITANO, CPPSE.
Title: A comprehensive manually-curated compendium of bovine transcription factors.
Publisher: Scientific Reports, v. 8, p. 1-12, 2018.
Language: en
Notes: Article number: 13747. Na publicação: Adhemar Zerlotini, Luciana C. A. Regitano.
Keywords: DNA bovino
Expressão gênica
Gene expression in cattle
Description: Transcription factors (TFs) are pivotal regulatory proteins that control gene expression in a contextdependent and tissue-specific manner. In contrast to human, where comprehensive curated TF collections exist, bovine TFs are only rudimentary recorded and characterized. In this article, we present a manually-curated compendium of 865 sequence-specific DNA-binding bovines TFs, which we analyzed for domain family distribution, evolutionary conservation, and tissue-specific expression. In addition, we provide a list of putative transcription cofactors derived from known interactions with the identified TFs. Since there is a general lack of knowledge concerning the regulation of gene expression in cattle, the curated list of TF should provide a basis for an improved comprehension of regulatory mechanisms that are specific to the species.
NAL Thesaurus: Gene expression regulation
Data Created: 2018-12-20
Appears in Collections:Artigo em periódico indexado (CNPTIA)

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