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Serological methods are valuable diagnostic tools for bovine brucellosis, a zoonotic infectious disease with a worldwide distribution. Currently employed diagnostic methods utilize crude bacterial extract or regions of LPS, a molecule that can exhibit cross-reactions with other infectious agents. The&...
O feijão guandu (Cajanus cajan) apresenta potencial como alternativa forrageira para o semiárido brasileiro devido à sua rusticidade e ao elevado teor de proteína bruta. No entanto, sua ensilagem enfrenta desafios relacionados à elevada capacidade tampão, que compromete a eficiência fermentativa....
The reduction of enteric methane emissions from ruminants is a central topic in research on sustainable livestock research. Feed additives targeting the rumen microbiome are among the strategies being explored to reduce methane emissions and improve nutrient efficiency. In this context, the&...
The NIBDAF is a biocompatible immunomodulatory target-delivery system designed to enhance immune responses without inducing cytotoxicity (intellectual property protection in progress). The use of tick-derived immunogens encapsulated in NIBDAF is a promising strategy for modulating immune responses against ...
Long COVID is a chronic condition that may develop after SARS-CoV-2 infection. Symptoms range from mild to severe, including respiratory, neurological and thrombotic complications, and lasting weeks, months or years. Long-term effects could result in disabilities, and to understand the mechanisms...
Obesity is a chronic low-grade inflammatory condition associated with increased thrombotic risk. Vitamin D deficiency is frequently observed as a factor that aggravates the inflammatory and procoagulant profile in obese individuals. Our aim was to investigate the influence of vitamin D on&#x...
Os corantes são amplamente utilizados como indicadores ácido-base, uma vez que alteram sua coloração de acordo com o pH do meio em que se encontram. Com base nessa característica, este estudo examinou o uso do extrato aquoso de capim-elefante roxo (Cenchrus purpureus) como possível...
The global need for affordable and scalable immunoprophylaxis strategies against SARS-CoV-2 has renewed interest in bovine colostrum as a source of neutralizing antibodies. This study aimed to evaluate the immunogenicity and neutralizing capacity of colostrum from cows immunized with SARS-CoV-2 r...
Hyperimmune bovine colostrum has emerged as a scalable and safe source of neutralizing antibodies for passive mucosal immunization. The quality and persistence of antibody responses are influenced by the choice of adjuvants. A phagocyte target delivery immunomodulatory nanosystem (NIBDAF; ongoing ...
A descoberta da penicilina no início do século passado deu início à era dos antibióticos e contribuiu para transformar o mundo rapidamente. Até então, feridas que infecionavam eram praticamente uma sentença de morte para o paciente, enquanto aglomerados humanos ou animais eram ambientes...